Which Flow Cytometry Service Do We Offer?
Discover Our Comprehensive Suite of Flow Cytometry-Based Assays To Accelerate Drug Development and Discovery!
Immune Cell and CAR-T Phenotyping
- Identify And Characterize Different Types Of Immune Cells – T Cells (Cytotoxic T Cells, Helper T Cells, Regulatory T Cells), NK Cells, B Cells, Dendritic Cells, Monocytes, Macrophages, Granulocytes.
- Pharmacokinetic Assessment Of CAR-T Therapies.
Intracellular Cytokine/Chemokine/Protein Analysis
- Measure The Expression Of Various Cytokines Or Chemokines Inside The Cell To Monitor The Stimulation/Activation Status Of Immune Cells.
- Assess Expression Of Kinases And Other Pharmacodynamic Markers Impacted By Therapy
Cellular Health And Function Measurements
- Assess Cell Cycle Status, Cell Proliferation, Apoptosis and Cytotoxicity.
- Assess Cellular Function By Measurement Of Phosphorylated proteins (Phosphoflow)
Immunogenicity Assessment
- Cell-Mediated Immune Response To Understand Immunomodulation By Therapeutic Agents.
- Antibody-Mediated Immune Response/ Neutralizing Antibodies Against MAbs, CAR-T or Gene Therapies.
Receptor Occupancy (RO) And Target Validation
- Receptor (RO) and Target Occupancy Assays To Assess PKPD, MOA And Safety.
- Validate Target Through Assessment By Functional Receptor Occupancy and Receptor Modulation Assays.
Immunoassays (Bead-Based)
- Detect and quantify the levels of immunoglobulins, human neutrophil antigens (HNAs), Human leukocyte antigens (HLAs), and human platelet antigens (HPAs) To Assess Immunogenicity, Transfusion Reactions, Autoimmune Diseases, and Alloimmunization.
- Measure Biomarkers/Cytokines in Serum, Plasma, Tissue/Cell Lysates, Cell Culture Media and other biofluids