Discovery Screening And Series Hit Confirmation
- Compound series screened and confirmed with clean concentration response data, ranked
- Assay formats matched to the target, biochemical or cell based, without a kit catalog
Services
Platforms
Solutions
About Us
Resources
De-Risk Your Analytical Testing, Formulation to Release.
Brief PhDs on your product, endpoints and stage.- Discovery Screening, IC50 Ranking And Quantitation Without The Regulated Overhead
- Twelve LC-MS, HPLC-UV, Immunoassay And PCR Platforms Behind Every Research Answer
- Two To Four Weeks From Signature To Results On Small And Mid Sized Study Projects
- A Planned Upgrade Path To GLP, So Research Methods Grow Into Regulated Submissions
Regulated And Inspected By:
Research Pace And Price, In A Regulated Lab
Early questions get fast turnaround at a lower fee on the same twelve LC-MS systems and readers that run our GLP studies. The method can move to GLP when your program does.
Cell-Free Biochemical And Binding Kinetics Assays
- Kinase, protease and receptor ligand assays, with binding kinetics measured in house
- IC50 and affinity series ranked reproducibly, with the honest biochemical to cellular gap
Analytical Quantitation From LLOQ Through ULOQ
- Calibration curves, sensitivity and selectivity established with acceptance criteria stated
- The quantitation discipline of a regulated lab, applied at research pace and pricing
Research Grade PK And Exposure Checks By LC-MS
- Plasma and tissue exposures for pilot and discovery studies, minus the GLP documentation
- The same LC-MS fleet and scientists, so numbers stand when the program moves forward
Personal Care And Consumer Product Testing
- Actives, preservatives and label claims quantified for personal care and consumer R&D
- Regulated pharma discipline behind non pharma questions, documented so results hold up
The Upgrade Path To GLP, Planned From Day One
- Methods built so tightening to GLP validation is a step, never a restart or a rebuild
- When the IND appears on your calendar, the method and the lab are already qualified
The Questions We Get Hired To Answer
We measure potency, purity, stability and cell exposure by HPLC or LC-MS against stated criteria.
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How Potent Is It
IC50 and ranking on biochemical or cell-based formats, comparable plate to plate
Biochemical Assay -
How Much Is In There
Content, purity and impurity by HPLC or LC-MS, against stated criteria
HPLC Testing Services -
Is It Stable
Plasma, matrix and formulation stability before an artifact misleads anyone
Ready To Start? Scope Your Analytical Testing.
Tailored analytical testing quote in 2 days.
Research Speed Should Not Mean Research You Cannot Reproduce Later
Odd samples fail on intake assumptions. We characterize the matrix first, then design the assay to it, instead of forcing it through a template.
Talk Science First? Ask Our Analytical Experts.
Discuss product, endpoints and stage.- Small and mid sized projects run signature to results in two to four weeks, priced per assay and per sample with no minimum batch, so a pilot question costs what a pilot question should.
- The instruments are the regulated fleet, twelve LC-MS with immunoassay and PCR platforms behind them, so research numbers do not dissolve when a development team reruns the work.
- Methods are written down like they will be validated one day, because many are: the upgrade to GLP is a planned step here, not a fresh start at a second laboratory you must requalify.
2-4Weeks From Signature To Results On Small Projects
~30%Of Sponsors Beyond Biotech: Institutes, Government, CROs
What Does Analytical Testing Cost?
Research tier pricing, per assay and per sample with no minimum batch size, and the quote states the tier so you are never paying for a QAU audit a screening question does not need. Small projects run signature to results in two to four weeks, and a senior scientist replies within two business days.
No Project Is Too Small To Start
Pilot studies and proof-of-concept questions are welcome here, and they are how many of our longest sponsor relationships began. The regulated pages carry the mid-study cost lock; this one carries a promise sized to research: start small, scale when it works.
Sponsors On Research That Earned The Next Study
Two thirds of the 100+ sponsors we work with each year return, and research-tier work earns that only when it holds up later.
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VP, Clinical Stage Biotech
There is also a willingness to develop new services to meet our needs even if not currently offered.
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Head, Bioanalytical Development
NorthEast BioLab goes the extra mile. We look forward to more meaningful collaborations.
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CRO Partner
Really appreciate the Co-Presidents’ hands-on approach.
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Co-Founder, Biotech & University PI
NorthEast BioLab tremendously supported us in reproducing our critical lab discoveries for drug metabolism
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Director, PK
We worked closely to implement the most efficient and cost-effective bioanalytical assay for our PK Studies.
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Scientist, Clinical Stage Biotech
I appreciate your team’s willingness to answer questions and provide guidance.
Release, Stability or Characterization? Tell Us Which.
Share the product and endpoints. We'll build the panel.Why Research Teams Bring Us The Questions Their Programs Turn On
The discipline came from two decades of regulated bioanalysis. The pace and pricing came from serving discovery teams who cannot wait a quarter for a number.
What You Receive
- Ranked, reproducible results with methods documented well enough to hand to development
- IC50, affinity and exposure numbers that carry stated acceptance criteria, never guesswork
- Data formatted for reuse, so the discovery record feeds the IND story when it arrives
- A quote that names the tier and says plainly when regulated overhead is not required
What We Need From You
- The question in a sentence, since the assay format follows it rather than a catalog
- Compound or product with what is known about it, purity and vehicle constraints included
- Any prior data worth matching, so plates bridge to your history instead of ignoring it
- Your decision date, because two to four weeks only helps if it lands before the meeting
A Complete Guide To Achieve Reliable Quantitative LC-MS Measurements
Liquid chromatography-mass spectrometry (LC-MS) combines two highly selective techniques for isolating, measuring, and quantifying analytes in complex mixtures. The LC component differentiates analytes based on their physicochemical characteristics….
One Synthetic Peptide, Purity To Potency: A Representative Path, Step By Step
One sample crosses three platforms to confirm how clean it is, how much is present and whether it still binds.
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1. The Peptide Arrives
A synthetic peptide with a claim to check: purity, content and whether it still binds
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2. Purity By HPLC
Purity and related impurities resolved by HPLC, supplier lots compared side by side
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3. Content Against Label
Assay against the stated content with criteria fixed before anyone sees a number
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4. Potency Confirmed
Biochemical binding or activity readout confirms the molecule does what its spec says
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5. Stability Answered
Solution and matrix stability read out before an artifact misleads the program
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6. Decision Delivered
One report: purity, content, potency and stability, formatted to be challenged
Why Do Buyers Choose Our Lab For Non-Standard Samples?
Because the method is built to your sample rather than the nearest catalog entry, and you talk to the chemist doing the work.
Get Your Testing Plan Reviewed By PhD Scientists.
Send your plan. We'll flag pitfalls before they cost you.- The regulated fleet at research pricing: twelve LC-MS, immunoassay and PCR all on site
- Two to four weeks signature to results, per assay pricing, batches accepted as they come
- An upgrade path to GLP that is a step, not a restart, when your program earns its IND
- About 30% of the work comes from beyond biotech: pharma, institutes, government, CROs
Regulated And Inspected By:
Research Answers You Will Not Have To Buy Twice When The Program Gets Serious
Send the question and the compound. A senior scientist matches the format, names the tier and quotes, on the platforms linked below.
Related FAQs
What buyers ask when their sample does not fit a form, answered.
Is this the same lab that runs your GLP studies?
What kinds of work fit under analytical testing?
Do you test personal care and consumer products?
When should we pay for GLP instead?
Can a research method graduate to GLP later?
How fast is a typical project?
Explore More Solutions
One unusual sample often reveals a recurring need, which we can take on as a standing program.
