List of Biomarker Assay

Biomarker research, discovery, and qualification are pivotal in modern drug development from demonstrating proof-of-concept (POC) to establishing drug safety and efficacy in the clinic. Our scientists meticulously follow and optimize your biomarker assay protocols from sample preparation to testing and reporting for high quality and reproducible biomarker analysis. NorthEast BioLab has significant expertise in single and multiplex analyte quantitation using LC-MS/MS, ELISA, MSD, Luminex, and qPCR. Below, please see a representative list of biomarkers available to be examined by us for your drug R&D in a variety of therapeutic areas, including aging, cancer, cardiovascular, immuno-oncology, immunology, inflammation, metabolism/obesity, neurobiology, etc.

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5'NT/CD73 - Rat
6Ckine/CCL21/Exodus-2
α-1-Acid Glycoprotein (AGP)
α-1-Acid Glycoprotein (AGP) - Mice
α-1-Acid Glycoprotein (AGP) - Rat
α-1-Antitrypsin (A1AT)
α-2-Macroglobulin
α-2-Macroglobulin - Mice
α-2-Macroglobulin (A2M) - Rat
α-Fetoprotein (AFP)
α-MSH - Mice
α-MSH - Rat
α-Synuclein
β-2-Microglobulin - Mice
β-2-Microglobulin - Rat
β-Endorphin - Mice
β-Endorphin - Rat
β-NGF
β2-Glycoprotein

A2M
A2M - Rat
Ab (Total)
ACTH
ACTH - Mice
ACTH - Rat
ADAM15
ADAMTS13
Adiponectin
Adiponectin - Mice
Adiponectin - Rat
Adipsin/Factor D
Adipsin/Factor D - Mice
Agouti-Related Protein (AgRP)
AGP
Akt - Rat
Akt (pS473) - Rat
Albumin - Rat
ALDH1A1
Alpha-amylase 1
Amphiregulin - Mice
Amylin (active)
Amylin (active) - Mice
Amylin (active) - Rat
Amylin (total)
Angiogenin (ANG)
Angiopoietin-1
Angiopoietin-2
Angiopoietin-2 - Mice
Angiostatin/Kringle
ANGPTL3
ANGPTL4
ANGPTL6
Annexin A1
Antithrombin III
Apelin
Apo AI
Apo AII
Apo B
Apo CII
Apo CIII
Apo E
ApoE4
ARG1 - Rat
Aβ38 (4G8)
Aβ38 (4G8) - Mice
Aβ38 (4G8) - Rat
Aβ38 (6E10)
Aβ40 (4G8)
Aβ40 (4G8) - Mice
Aβ40 (4G8) - Rat
Aβ40 (6E10)
Aβ42
Aβ42 (4G8)
Aβ42 (4G8) - Mice
Aβ42 (4G8) - Rat
Aβ42 (6E10)

B2M
B2M - Rat
BAFF - Mice
BAFF-R
BAFF/Blys
BCA-1/BLC - Mice
BCA-1/CXCL13
BCMA
BDNF
BDNF - Mice
BDNF - Rat
Betacellulin - Mice
BMP-9
BNP
BNP - Rat
BRAK / CXCL14
BTLA

c-Jun - Rat
C-Peptide
c-Peptide - Mice
C-Peptide - Rat
C-Peptide 2 - Mice
C-Peptide 2 - Rat
C1q
C2
C3
C4
C4b
C5
C5a
C9
CA1
CA125
CA15-3
CA19-9
CA50
Cadherin 13 (CDH13)
Calbindin
Calprotectin
cAMP
cAMP - Mice
cAMP - Rat
Cancer Antigen 125
Carbonic Anhydrase 9 (CA9)
Cardiac Troponin I (cTnI) - Rat
Cardiac Troponin T (cTnT) - Rat
Cathepsin D
Caveolin-1 - Rat
CCL28
CD27
CD28
CD31/PECAM-1
CD40
CD44
CD5
CD80/B7-1
CD86/B7-2
CEA
CENP-A (Centromere Protein A)
CENP-B (Centromere Protein B
CHO (HCP)
CHOP - Rat
Chromogranin-A (CHGA/CGA)
CK-MB
Clusterin
Clusterin - Mice
Clusterin - Rat
CNTF
Complement C9
Complement Factor C3
Complement Factor D
Complement Factor H (CFH)
Connective Tissue Growth Factor (CTGF) - Rat
Corin/ATC2
Corticosterone - Rat
Cortisol
Cortisol - Mice
Creatine Kinase Muscle (CKM) - Rat
CRP
CRP - Mice
CTACK/CCL27
CTACK/CCL27 - Mice
CTLA-4/CD152
CXCL16
CXCL16 - Mice
CXCL6/GCP-2
CYFRA21-1
Cystatin C
Cystatin C - Mice
Cystatin C - Rat
Cytokeratin-8

D-dimer
DJ-1/PARK7
DKK1
DKK1 - Mice
DKK1 - Rat
dPAPP-A
DPP4
DPPIV

E-Cadherin
E-Selectin
EGF
EGF - Mice
EGF - Rat
ENA-78
ENA-78/CXCL5
Endocan-1 (ESM-1)
Endocan-1 (ESM-1) - Mice
Endoglin
Endoglin - Mice
Endostatin
Endothelin-1
Endothelin-1 - Mice
Enolase 2
Eotaxin-2/CCL24/MPIF-2
Eotaxin-3/CCL26
Eotaxin/CCL11
Eotaxin/CCL11 - Mice
Eotaxin/CCL11 - Rat
EpCAM
ERK-1/2 - Rat
ERK-1/2 (pT202/pY204) (pT185/pY187) - Rat
Erythropoietin (EPO)
Erythropoietin (EPO) - Mice
Erythropoietin (EPO) - Rat
Estradiol
Estradiol - Mice
Exodus-2/CCL21/6Ckine - Mice
Extracellular Matrix Protein 1 (ECM1)

FABP1
FABP3
FABP3 - Mice
FABP3 - Rat
FABP4
Factor (PLGF-2) - Mice
Factor B
Factor H
Factor I
Factor P/Properdin
Factor VII
Fas
FasL
Ferritin
Fetuin A
FGF-1/FGF-acidic
FGF-19
FGF-2 / FGF-basic
FGF-2/FGF-basic
FGF-2/FGF-basic - Mice
FGF-21
FGF-21 - Mice
FGF-21 - Rat
FGF-23
FGF-23 - Mice
FGF-23 - Rat
Fibrinogen
Fibrinogen - Rat
Fibroblast Activation Protein (FAP)
Flt-1/VEGFR1
Flt3 Ligand
Follistatin (FST)
Follistatin (FST) - Mice
Follistatin-like - Mice
Follistatin-like Protein 1 (FSTL1) - Rat
FOXO3α (pT32) - Rat
Fractalkine/CX3CL1
Fractalkine/CX3CL1 - Mice
Fractalkine/CX3CL1 - Rat
FSH
FSH - Mice
FSH - Rat
FSTL1

G-CSF
G-CSF - Mice
G-CSF - Rat
Galectin-3
GDF-11
GDF-15
Gelsolin
GFAP
GH
GH - Mice
GH - Rat
Ghrelin (active)
Ghrelin (active) - Mice
Ghrelin (active) - Rat
GIP (active)
GIP (inactive)
GIP (total)
GIP (total) - Mice
GIP (total) - Rat
GITR
GITRL
GLP-1 (active)
GLP-1 (active) - Mice
GLP-1 (active) - Rat
GLP-1 (total)
GLP-1 (total) - Mice
GLP-1 (total) - Rat
GLP-1 (x-36) amide - Mice
GLP-1 (x-36) amide - Rat
Glucagon
Glucagon - Mice
Glucagon - Rat
GM-CSF
GM-CSF - Mice
GM-CSF - Rat
GnRH
GnRH - Mice
GOT1 - Rat
GP130 (soluble)
Granzyme A
Granzyme B
Granzyme B - Mice
GRO
GROα
GROα/KC/CINC-1/CXCL1 - Rat
GSK-3β - Rat
GSK-3β (pS9) - Rat
GSTα - Rat

Haptoglobin
Haptoglobin - Mice
Haptoglobin - Rat
HB-EGF
HCC-4 / CCL16
HCGβ
HE4
Hepsin
HGF
HGF - Mice
HIF-1α - Rat
Histone H3 (pS10) - Rat
HMGB1
HSP60
HSP70
Human Serum Albumin (HSA)
HVEM

I-309/CCL1
I-TAC / CXCL11
ICAM-1
ICAM-3
ICOS
IFNα - Mice
IFNα2
IFNβ
IFNβ1 - Mice
IFNγ
IFNγ - Mice
IFNγ - Rat
IgA
IgA - Mice
IgE
IgE - Mice
IGF-1
IGF-2
IGF1R
IGFBP1
IGFBP2
IGFBP3
IGFBP4
IGFBP5
IGFBP6
IGFBP7
IgG
IgG1
IgG1 - Mice
IgG2
IgG2a - Mice
IgG2b - Mice
IgG3
IgG3 - Mice
IgG4
IgM
IgM - Mice
IL-10
IL-10 - Mice
IL-10 - Rat
IL-11 - Mice
IL-12 - Mice
IL-12 (p40)
IL-12 (p40) - Mice
IL-12 (p70)
IL-12 (p70) - Mice
IL-12 (p70) - Rat
IL-13
IL-13 - Mice
IL-13 - Rat
IL-14 / α-Taxilin
IL-15
IL-15 - Mice
IL-15 - Rat
IL-16
IL-16 - Mice
IL-17A (Gen. B)
IL-17A/CTLA8
IL-17A/CTLA8 - Mice
IL-17A/CTLA8 - Rat
IL-17A/F
IL-17A/F - Mice
IL-17B
IL-17C
IL-17C - Mice
IL-17D
IL-17E/IL-25
IL-17E/IL-25 - Mice
IL-17F
IL-17F - Mice
IL-18
IL-18 - Rat
IL-19
IL-1RA
IL-1α
IL-1α - Mice
IL-1α - Rat
IL-1β
IL-1β - Mice
IL-1β - Rat
IL-2
IL-2 - Mice
IL-2 - Rat
IL-20
IL-20 - Mice
IL-21
IL-21 - Mice
IL-22
IL-22 - Mice
IL-23
IL-23 - Mice
IL-24
IL-27
IL-27 - Mice
IL-27p28/IL-30 - Mice
IL-28A/IFNλ2
IL-28B / IFNλ3
IL-28B/IFNλ3 - Mice
IL-29/IFN-l1
IL-2Ra
IL-3
IL-3 - Mice
IL-31
IL-31 - Mice
IL-32α
IL-33/NF-HEV (mature)
IL-33/NF-HEV(mature) - Mice
IL-34
IL-35
IL-36β/IL-1F8
IL-37/IL-1F7
IL-38/IL-1F10
IL-4
IL-4 - Rat
IL-4 – Mice
IL-5
IL-5 - Mice
IL-5 - Rat
IL-6
IL-6 - Mice
IL-6 - Rat
IL-6R
IL-7
IL-7 - Mice
IL-8 (HA)
IL-8/CXCL8
IL-9
IL-9 - Mice
Insulin
Insulin - Mice
Insulin - Rat
Involucrin
IP-10/CXCL10
IP-10/CXCL10 - Mice
IP-10/CXCL10 - Rat
IRE-1α (CXCL11) - Rat
Irisin
Irisin - Mice
Irisin - Rat

Jag1
Jag1 - Mice
Jo-1

Kallikrein-6
KC/CXCL1 - Mice
KC/GRO - Rat
KC/GROα/CXCL1 - Mice
Keratin-1,10
Keratin-6
KIM-1 - Mice
KIM-1/TIM-1/HAVCR
KIM-1/TIM-1/HAVCR - Rat
Ku

Lactotransferrin (LTF)
LAG-3
LBP
LDLR
Leptin
Leptin - Mice
Leptin - Rat
Leptin Receptor (LEPR)/OB-R
LH
LH - Mice
LH - Rat
LIF
LIF - Mice
LIF - Rat
LIGHT
LIGHT - Mice
LIX - Mice
LIX - Rat
LRG1
LRRK2 (pS935)

M-CSF
M-CSF - Mice
Mannose-binding Lectin (MBL)
MCAM/MUC18
MCP-1/CCL2
MCP-1/CCL2 - Mice
MCP-1/CCL2 - Rat
MCP-2/CCL8
MCP-3/CCL7
MCP-4/CCL13
MCP-5/CCL12 - Mice
MDC/CCL22
MDC/CCL22 - Mice
MDM2 (ubiquitinylated) - Rat
MEK 1/2 - Rat
MEK 1/2 (pS217/pS221) - Rat
MEK2 - Rat
Melanoma Inhibitory Activity (MIA)
Melatonin - Rat
Mesothelin
MET (soluble)
Mi-2
Midkine
MIF
MIG/CXCL9
MIG/CXCL9 - Mice
MIP-1α/CCL3
MIP-1α/CCL3 - Mice
MIP-1α/CCL3 - Rat
MIP-1β/CCL4
MIP-1β/CCL4 - Mice
MIP-1δ/MIP-5/CCL15
MIP-2/CXCL2 - Mice
MIP-2/CXCL2 - Rat
MIP-3α (CCL20) - Rat
MIP-3α / CCL20
MIP-3α/CCL20 - Mice
MIP-3β/CCL19
MIP-3β/CCL19 - Mice
MIP-4/PARC/CCL18
MIP-5/CCL15
MMP-1
MMP-10
MMP-12
MMP-12 - Mice
MMP-13
MMP-2
MMP-2 - Mice
MMP-3
MMP-3 - Mice
MMP-7
MMP-8
MMP-8 - Mice
MMP-9
MMP-9 (total) - Mice
MPIF/CCL23
MR-ProADM
mTOR (pS2488) - Rat
Myeloperoxidase (MPO)
Myoglobin
Myosin Light Chain 3 (MYL3) - Rat
Myostatin/GDF8
Myostatin/GDF8 - Mice
Myostatin/GDF8 - Rat

NCAML1/L1CAM/CD171
Nectin-4
Neurogranin (NRGN)
Neuron-specific Enolase (NSE)
Neurotensin - Mice
Neurotensin - Rat
Neutrophil Elastase-2 (ELA2)
NFkB (pS468) - Rat
NFkB (pS536) - Rat
NGAL/Lipocalin-2
NGAL/Lipocalin-2 - Mice
NGAL/Lipocalin-2 - Rat
NGF
Notch1
Notch1 - Mice
NT proBNP
NT-proANP - Rat
NT-proBNP - Rat

Oncostatin M (OSM) - Mice
Oncostatin-M (OSM)
Osteoactivin
Osteocalcin - Rat
Osteocalcin (OC)
Osteocrin (OSTN)/Musclin
Osteocrin (OSTN)/Musclin - Mice
Osteocrin (OSTN)/Musclin - Rat
Osteonectin/SPARC
Osteonectin/SPARC - Mice
Osteonectin/SPARC - Rat
Osteopontin (OPN)
Osteopontin (OPN) - Mice
Osteopontin (OPN) - Rat
Osteoprotegerin (OPG)
Osteoprotegerin (OPG) - Mice
Osteoprotegerin (OPG) - Rat
OX40
OX40L
Oxytocin - Mice
Oxytocin - Rat

P-Cadherin
P-Selectin
p38 - Rat
p38 (pT180/pY182) - Rat
p53 - Rat
p53 (pS15) - Rat
p53 (ubiquitinylated) - Rat
p62 (SQSTM1) - Rat
p70S6K - Rat
p70S6K (pT389) - Rat
p70S6K (pT421/pS424) - Rat
PAI-1 (total)
PAI-1 (total) - Mice
PAI-1 (total) - Rat
Pancreatic - Mice
Pancreatic Polypeptide (PP)
Pancreatic Polypeptide (PP) - Rat
PARK5/UCHL1
PARK7/DJ1
PCNA (Proliferating Cell Nuclear Antigen A)
PD-1
PD-L1
PD-L2
PDGF-AA
PDGF-AB/BB
PEDF
Pentraxin-3 (PTX3)
Perforin
Periostin
PERK - Rat
pGRN
PL-12 (Alanyl-tRNA Synthetase)
PLA2G7
Placental Growth - Mice
Placental Growth Factor (PLGF)
Platelet Factor 4 (PF4)/CXCL4
Pleckstrin - Rat
PlGF
PLGF-2 - Mice
PM/Sci 100
Polypeptide (PP) - Mice
PRAS40 - Rat
PRDX-1
PRDX6
PRNP (Prion Protein)
Progesterone
Progesterone - Mice
Prolactin
Prolactin - Mice
Prolactin - Rat
proMMP-9 - Mice
Protein 1 (FSTL1) - Mice
Protein A
Proteinase 3
PSA (free)
PSA (total)
PSD-95 - Rat
PSGL-1
pTau (Thr181)
PTGDS
PTH
PTH - Rat
PYY (active)
PYY (total)
PYY (total) - Mice
PYY (total) - Rat

RANKL
RANTES/CCL5
RANTES/CCL5 - Mice
RANTES/CCL5 - Rat
RBP4
Renin - Mice
Resistin
Resistin - Mice
Resistin - Rat
Ribosomal P
RNP (Ribonucleoprotein)
RNP/Smith (RNP/ Sm)

S100A12
S100A8/MRP8
S6RP - Rat
SAA
sALK-1 - Mice
sAPPa
sAPPb (Swedish variant)
sAPPb (wild type)
sAPPβ (wild type) - Mice
sAXL
SB/La (Sjögren’s Syndrome-related antigen B/La)
sc-Kit/sStem Cell Factor Receptor (SCFR)
sCD137/4-1BB/ - Mice
sCD137/4-1BB/TNFRSF9
sCD14
sCD163
sCD30
sCD30 - Mice
sCD31/sPECAM-1
sCD31/sPECAM-1 - Mice
sCD40L
sCD40L - Mice
SCF
Scl-70
Sclerostin (SOST)
Sclerostin (SOST) - Mice
Sclerostin (SOST) - Rat
SDF-1/CXCL12
SDF-1/CXCL12 - Mice
SDF-1a
SDH - Rat
sE-Selectin
sE-Selectin - Mice
sE-Selectin - Rat
Secretin - Mice
sEGFR/sHER1/ErbB1
Serpin A1
Serpin A12/ Vaspin
Serum Amyloid A
Serum Amyloid P (SAP)
Serum Amyloid P (SAP) - Mice
Sex Hormone Binding Globulin (SHBG)
sFAS/TNFRSF6
sFas/TNFRSF6 - Mice
sFasL
sFasL - Mice
sGP130
sGP130 - Mice
sHER2/sEGFR2/ sErbB2
sHER3/sEGFR3/ sErbB3
sHGFR/sc-Met
sICAM-1
sICAM-1 - Mice
sICAM-1 - Rat
sIL-1RI
sIL-1RI - Mice
sIL-1RII
sIL-1RII - Mice
sIL-2Rα
sIL-2Rα - Mice
sIL-4R
sIL-4R - Mice
sIL-6R
sIL-6R - Mice
sIL-6Rα
sL-Selectin
Sm
sNCAM
sNeuropilin-1 (sNRP-1)
sP-Selectin
sP-Selectin - Mice
sRAGE
sRAGE - Mice
SSA/Ro52 (Sjögren’s Syndrome-related antigen A/Ro52 kDa)
SSA/Ro60 (Sjögren’s Syndrome-related antigen A/Ro60 kDa)
sST2/IL1RL1
STAT3 - Rat
STAT3 (pY705) - Rat
STAT4 - Rat
STAT4 (pY693) - Rat
STAT5a/b - Rat
STAT5a/b (pY694) - Rat
sTIE-2
sTNF RI
sTNF RI - Mice
sTNF RII
sTNF RII – Mice
sTroponin I (sTnI) - Rat
Substance P - Mice
Substance P - Rat
suPAR
sVCAM-1
sVEGFR1/sFlt-1
sVEGFR1/sFlt-1 - Mice
sVEGFR2/sKDR/sFlk-1
sVEGFR2/sKDR/sFlk-1 - Mice
sVEGFR3/sFlt-4
sVEGFR3/sFlt-4 - Mice
Syndecan 4 (SYND4)

T3
T3 - Mice
T3 - Rat
T4
T4 - Mice
T4 - Rat
TARC/CCL17
TARC/CCL17 - Mice
Tau - Mice
Tau (pT181)
Tau (pT181) - Mice
Tau (pT231)
Tau (pT231) - Mice
Tau (total)
Tenascin-C (TN-C)
Testosterone
Testosterone - Mice
TFF3
TfR-1 (soluble)
TGFα
TGFβ1
TGFβ1 - Mice
TGFβ1 - Rat
TGFβ2
TGFβ2 - Mice
TGFβ2 - Rat
TGFβ3
TGFβ3 - Mice
TGFβ3 - Rat
Thrombomodulin
Thrombomodulin - Mice
Thrombospondin-1 (TSP-1)
Thrombospondin-2 (TSP-2)
Tie-2
TIM-3
TIMP-1
TIMP-1 - Mice
TIMP-1 - Rat
TIMP-2
TIMP-3
TIMP-4
Tissue Factor (TF)
TLR-1
TLR-2
TNF-RI
TNF-RI - Mice
TNF-RII
TNFRSF10C
TNFRSF9 - Mice
TNFα
TNFα - Mice
TNFα - Rat
TNFβ/Lymphotoxin-α (LTA)
TNFβ/Lymphotoxin-α (LTA) - Mice
TPO
TRAIL/TNFSF10
Transglutaminase 2 (TGM2)
TRAP5
TREM2
Troponin I (TnI)
Troponin I (TnI) - Mice
Troponin ITC Complex - Rat
Troponin T (TnT)
Troponin T (TnT) - Mice
TSH
TSH - Mice
TSH - Rat
TSLP
TSP-1 - Rat
TWEAK

ucMGP

VEGF - Rat
VEGF-A
VEGF-A - Mice
VEGF-A - Rat
VEGF-C
VEGF-C - Mice
VEGF-D
VEGF-D - Mice
VEGF-R2
VILIP-1
Vitamin D Binding Protein
vWF

Wnt3a - Rat

XBP-1 - Rat

YKL40/CHI3L1

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List of Biomarker Assay

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List of Biomarker Assay

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