What are G-CSF Functions and Effects?
Understanding the functions and effects of G-CSF
G-CSF promotes the maturation process of neutrophils through survival, proliferation, differentiation, etc. There are two natural forms of the human glycoprotein, 174 and 177- amino-acid-long protein of molecular weight 19,600 grams per mole. Below, we have listed the primary categories of G-CSF:
- lenograstim (Granocyte)
- filgrastim (Neupogen, Zarzio, Nivestim, Ratiograstim)
- long-acting (pegylated) filgrastim (pegfilgrastim, Neulasta) and pegfilgrastim (Lonquex)
long-acting (pegylated) filgrastim (pegfilgrastim, Neulasta) and pegfilgrastim (Lonquex)
Typically, G-CSF pharmaceutical products utilize the more active 174 amino acid form by recombinant DNA (rDNA) technology. Furthermore, we have included the Granulocyte Colony Stimulating Factor (G-CSF) mechanism on the following –