Drug Metabolism and Pharmacokinetics (DMPK)

  • Absorption, distribution, metabolism, and excretion (ADME) studies
  • Pharmacokinetics (PK) studies
  • Toxicokinetics (TK) / Safety assessment studies
  • Dose range finding
  • Metabolic Stability
  • Plasma Protein Binding Determination
  • Blood Plasma Partitioning
  • Cytochrome P450 (CYP) Induction
  • CYP Inhibition
  • Pharmacokinetic evaluation and reporting (WinNonlin)
  • Compartmental & noncompartmental analysis (NCA)