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Expertise

  • Menu IconAll Expertise
    • Menu IconMass Spectrometry (LC-MS)
      • Menu IconMass Spectrometry Services
      • Menu IconHPLC Testing Services
    • Menu IconMeso Scale Discovery Assay
      • Menu IconELISA Assay
        • Menu IconLuminex Multiplex Assay
      • Menu IconFlow Cytometry
        • Menu IconqPCR Analysis, ddPCR Assay
          • Menu IconWestern Blot, In Cell Western

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                • Menu IconDose Formulation Analysis
                • Menu IconPK PD Analysis
                • Menu IconDrug Metabolism and Pharmacokinetics (DMPK)
                • Menu IconADME Studies
                • Menu IconBioequivalence and Bioavailability Studies
              • Menu IconADA Assay, Neutralizing Antibody Assay
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                                              • Menu IconSr. Scientist – Cell Based Assay
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                                                            • Home
                                                            • Flow Cytometry

                                                            Advanced Flow Cytometry Service For Immunophenotyping, Receptor Occupancy, Cell Proliferation, Cytotoxicity, Or Characterization

                                                            Accelerate Your Flow Cytometry Testing With Our Expertise!

                                                            We’ll Connect Within 1 Business Day

                                                            • Comprehensive Immuno-Phenotyping To Assess Immune Cells And CAR-T Cells
                                                            • Identification Of Rare Population – Hematopoietic Stem Cells And Early Progenitor Cells
                                                            • Rapid Analysis of Cell Cycle, Cell Proliferation, Cytotoxicity And Functional Analysis
                                                            • Expert Analysis Of Bead-Based Immunoglobulin And Biomarker Analysis

                                                            Regulated And Inspected By:

                                                            Good Laboratory Practice for Nonclinical Laboratory Studies | NorthEast BioLab Food and Drug Administration (FDA | NorthEast BioLab Clinical Laboratory Improvement Amendments | NorthEast BioLab International Orgaization for Standardization |NorthEast BioLab
                                                            + Years Of Bioanalysis
                                                            + Small/Large Molecule Studies
                                                            + Custom Bioanalytical Assays
                                                            + Investigational Drugs
                                                            + Biomarker & Cytokine Assays

                                                            Which Flow Cytometry Service Do We Offer?

                                                            Discover Our Comprehensive Suite of Flow Cytometry-Based Assays To Accelerate Drug Development and Discovery!

                                                            Immune Cell and CAR-T Phenotyping

                                                            • Identify And Characterize Different Types Of Immune Cells – T Cells (Cytotoxic T Cells, Helper T Cells, Regulatory T Cells), NK Cells, B Cells, Dendritic Cells, Monocytes, Macrophages, Granulocytes.
                                                            • Pharmacokinetic Assessment Of CAR-T Therapies.

                                                            Intracellular Cytokine/Chemokine/Protein Analysis

                                                            • Measure The Expression Of Various Cytokines Or Chemokines Inside The Cell To Monitor The Stimulation/Activation Status Of Immune Cells.
                                                            • Assess Expression Of Kinases And Other Pharmacodynamic Markers Impacted By Therapy

                                                            Cellular Health And Function Measurements

                                                            • Assess Cell Cycle Status, Cell Proliferation, Apoptosis and Cytotoxicity.
                                                            • Assess Cellular Function By Measurement Of Phosphorylated proteins (Phosphoflow)

                                                            Immunogenicity Assessment

                                                            • Cell-Mediated Immune Response To Understand Immunomodulation By Therapeutic Agents.
                                                            • Antibody-Mediated Immune Response/ Neutralizing Antibodies Against MAbs, CAR-T or Gene Therapies.

                                                            Receptor Occupancy (RO) And Target Validation

                                                            • Receptor (RO) and Target Occupancy Assays To Assess PKPD, MOA And Safety.
                                                            • Validate Target Through Assessment By Functional Receptor Occupancy and Receptor Modulation Assays.

                                                            Immunoassays (Bead-Based)

                                                            • Detect and quantify the levels of immunoglobulins, human neutrophil antigens (HNAs), Human leukocyte antigens (HLAs), and human platelet antigens (HPAs) To Assess Immunogenicity, Transfusion Reactions, Autoimmune Diseases, and Alloimmunization.
                                                            • Measure Biomarkers/Cytokines in Serum, Plasma, Tissue/Cell Lysates, Cell Culture Media and other biofluids

                                                            Flow Cytometry Assay Services at NorthEast BioLab: Trust Our Deep And Diverse Expertise

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                                                            T-Cell Immuno-Phenotyping

                                                            Helper, Cytotoxic, Regulatory T Cells for Vaccines, Immunotherapies

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                                                            PBMC Immune Cell Monitoring

                                                            Distribution, Functional States of T/B/NK Cells, Monocytes, Etc.

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                                                            Intracellular Cytokine Stain

                                                            Immune Signaling, Inflammatory Response from Single-Cells

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                                                            Cell Cycle, Proliferation

                                                            CFSE/Edu Assay for Cell Growth, Division, and Cell Cycle

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                                                            NK Cytotoxicity, Cell Apoptosis

                                                            Cellular Health, Disease Mechanisms, and Therapeutic Effects

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                                                            Cell Receptor Occupancy

                                                            Ab-Target Binding for Efficacy, Safety, Pharmacodynamics (PD)

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                                                            CAR-T Cell Immunogenicity

                                                            Anti-CAR Humoral and Cellular Immune Response

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                                                            Phosphoflow Analysis

                                                            MOA/PD Biomarkers for Kinase Inhibitors, Checkpoint Blockers, Etc

                                                            Contact A Scientist to discuss Flow Cytometry Service details

                                                            We’ll Contact You Within 1 Business Day

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                                                            Instrument Image

                                                            Comprehensive Suite of Flow Cytometry-Based Assay Services To Exceed Your Expectations

                                                            Kick‑Start Your Flow Cytometry Assays At Our Agile Lab!

                                                            We’ll Reach Out Within 1 Business Day

                                                            • Your Flow Cytometry-Based Assays are crucial—avoid hidden pitfalls that could delay drug development.
                                                            • A responsive and flexible Flow Cytometry lab will accelerate your drug development process.
                                                            • Our Flow Cytometry expertise helps you advance in regulatory submissions without exceeding your budget.

                                                            20+

                                                            Years of Bioanalysis Services in Industry Leading Time

                                                            450+

                                                            Custom Bioanalytical Methods Completed Within Budget

                                                            Expected Services Turnaround

                                                            We whole-heartedly cooperate with your team to accomplish our shared goals and accelerate your Flow-Based study timeline. For example, we need just six-to-eight weeks for Flow-Based assay development and validation. Afterward, we need a couple of weeks for submitting your audited report with complete details of validation experiments. Here, we pull together our core strengths – scientific experience, regulatory expertise, and operational excellence – to make sure your resources and costs are optimized.

                                                            Requested Sponsor Input

                                                            Our team thrives on open lines of communication between sponsors and our frontline scientists, project managers, lab staff, etc. Could you please share additional details about your analyte(s), preferred critical reagents and Flow Cytometry assay supplies, current Flow Cytometry assay (s), data from previous run(s), study protocols (with # of cohorts, samples), etc to expedite outlining the scope of work for quotation and timeline estimation

                                                            Reviews From Sponsors of Our Flow-Based Assay Services

                                                            Sponsor
                                                            Head, Bioanalytical Development

                                                            “NorthEast BioLab goes the extra mile. We look forward to more meaningful collaborations.”

                                                            Sponsor
                                                            Sr. Dir., Bioanalytical Development & QC

                                                            NorthEast BioLab offers a science-based, hands-on approach to the latest bioanalytical platforms

                                                            Sponsor
                                                            VP, Bioanalytical Development

                                                            “NorthEast BioLab is the most responsive and thorough bioanalysis lab services CRO.”

                                                            Sponsor
                                                            VP, Development Operations

                                                            NorthEast BioLab’s scientists deliver high-quality data on time and within budget

                                                            Sponsor
                                                            VP, Biomarker Development 

                                                            NorthEast BioLab is a responsive, collaborative, and reliable partner

                                                            Sponsor
                                                            President & CSO, Biotech

                                                            We found their integrity as refreshing as readiness to provide creative scientific input and high-quality data

                                                            Unlock Precision, ROI With Our Flow Cytometry Service!

                                                            We’ll Respond Within 1 Business Day

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                                                            Efficiently Accelerate Flow Cytometry Analysis With Our Bioanalytical Experts At Your Terms

                                                            Expert Flow Cytometry Assay Development & Validation Services

                                                            • Comprehensive Assay Optimization & Validation: We optimize antibodies, voltages, compensation, and gating for clear, repeatable flow-cytometry signals every run
                                                            • Up-Front Technical & Regulatory Review: We dissect your current flow protocols, data sets, reagent inventory, and compliance goals to deliver a gap-analysis within 48 hours
                                                            • Rapid Tagging & Panel Design: In-house fluorescent-dye conjugation and custom panel design to deliver immune-phenotyping, cytokine, or functional assays on your timeline

                                                            Responsive Flow Cytometry CRO with Tailored Lab Services

                                                            • Agile Turnaround: Adaptive scheduling and staged data releases keep your program on track when priorities or sample counts shift
                                                            • Direct Collaboration with Senior Cytometrists: Real-time conversations on sample prep and troubleshooting keep potential issues from ever reaching the data table
                                                            • Decades-Deep QA & Submission Expertise: GLP/GCLP and FDA/EMA know-how ensures every validation report is formatted for seamless e-CTD integration
                                                            Bioanalytical Lab Services

                                                            Comprehensive Guide to Flow Cytometry: Principles, Process, and Applications

                                                            Flow cytometry is a laser-based laboratory bioanalytical technique to detect chemical and physical differences of cells and particles…

                                                            Facility Video
                                                            Read More

                                                            Our Streamlined Process For On-Time Delivery Of Entire Scope Of Work Within Sponsor Budget

                                                            Customer Inquiry Icon Experimental
                                                            Design
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                                                            Customer Inquiry Icon Cell
                                                            Preparation
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                                                            Customer Inquiry Icon Cell Staining
                                                            With Control
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                                                            Method Development Icon Instrument Setup
                                                            and Compensation
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                                                            Method Development Icon Event
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                                                            Method Development Icon Data Analysis
                                                            and Interpretation
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                                                            Why Choose Us For Your Flow Cytometry-Based Assay Development And Bioanalysis?

                                                            Proof-Of-Concept Driven, High Value Flow Cytometry Assay Development, Validation/Qualification And Sample Analysis!

                                                            Partner With Our Flow Cytometry Lab For Swift, Valuable Data!

                                                            We’ll Get Back to You Within 1 Business Day

                                                            • High-Throughput Analysis Of Immune Cells, CAR-T Cells, And Rare Cell Populations For Drug Development.
                                                            • Custom Assays For Biomarkers, Immunogenicity, MOA, And Pharmacodynamics Using Cytokines And Phosphoproteins.
                                                            • Study Protocol Support For Assay Design, Sample Collection, Biobanking, And Analysis.
                                                            • FDA-Audited, GLP Bioanalytical Lab For Drug Screening, Toxicity, And Biomarker Discovery.
                                                            • Good Laboratory Practice for Nonclinical Laboratory Studies | NorthEast BioLab
                                                            • Food and Drug Administration (FDA | NorthEast BioLab
                                                            • Clinical Laboratory Improvement Amendments | NorthEast BioLab
                                                            • International Orgaization for Standardization |NorthEast BioLab
                                                            • United States Drug Enforcement Administration | NorthEast BioLab
                                                            • Department of Consumer Protection | NorthEast BioLab

                                                            Support Your Drug Innovation With Latest Equipment In Safe Hands Of Our Bioanalysis Experts

                                                            We Judiciously Invest In Our People, Solutions And Infrastructure, And Regularly Review Our Business Processes And Practices To Exceed Sponsor Expectations

                                                            Pharmacokinetics (PK) Study

                                                            Toxicology (Tox) Study

                                                            Cytokine Analysis, Biomarker Assay

                                                            Bioequivalence and Bioavailability Studies

                                                            Explore More Expertise

                                                            • LC MS Method Development Lab | NorthEast BioLab Liquid Chromatography Mass
                                                              Spectrometry
                                                            • Meso Scale Discovery
                                                              Assay
                                                            • ELISA Assay Validation Lab | NorthEast BioLab ELISA
                                                              Assay
                                                            • Flow Cytometry
                                                            • Real Time Quantitative (qPCR) Analysis | NorthEast BioLab qPCR Analysis,
                                                              dPCR Assay
                                                            • Western Blot Assay,
                                                              In Cell Western Assay

                                                            Contact A Scientist With Your Bioanalytical Study Details

                                                            We Will Respond Within 1 Business Day

                                                            Expertise

                                                            Expertise

                                                            • Mass Spectrometry (LC-MS)
                                                            • Meso Scale Discovery Assay
                                                            • ELISA Assay
                                                            • Flow Cytometry
                                                            • qPCR Analysis, ddPCR Assay
                                                            • Western Blot, In Cell Western

                                                            Services

                                                            Services

                                                            • Pharmacokinetics (PK) Study
                                                            • ADA Assay, Neutralizing Antibody Assay
                                                            • Multiplex Cytokine Assay
                                                            • Biomarker Assay
                                                            • Cell-Based Assay
                                                            • Bioanalytical Assay Validation

                                                            Solutions

                                                            Solutions

                                                            • Clinical CRO
                                                            • GLP Laboratory
                                                            • Preclinical CRO
                                                            • Method Development, Validation, And Transfer
                                                            • Analytical Testing

                                                            About Us

                                                            About Us

                                                            • Overview
                                                            • Leadership
                                                            • Facility and Equipment
                                                            • Quality and Compliance
                                                            • Therapeutic Areas
                                                            • Why Us?
                                                            • Values
                                                            • Process
                                                            • Partners
                                                            • Careers

                                                            Resources

                                                            Resources

                                                            • Learning Center
                                                            • Blog
                                                            • Case Study
                                                            • Video Brochures
                                                            • News and Events
                                                            • Testimonials
                                                            • Contact Us
                                                            NorthEast BioLab Logo Agile Bioanalytical Services CRO
                                                            sales@nebiolab.comFollow Up On Email
                                                            (203) 361 3780Follow Up On Phone

                                                            35 Worth Ave, Hamden, CT 06518

                                                            • Good Laboratory Practice for Nonclinical Laboratory Studies | NorthEast BioLab
                                                            • Food and Drug Administration (FDA | NorthEast BioLab
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                                                            • United States Drug Enforcement Administration | NorthEast BioLab
                                                            • Department of Consumer Protection | NorthEast BioLab
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